Addition of vancomycin to cefazolin is often unnecessary for preoperative antibiotic prophylaxis during total joint arthroplasties

Table 3 Multivariate logistic regression for all cause infection

1-year	OR^a	95% CI	P-value
Sex	1.01	0.53–1.94	0.973
ASA Class	1.65	0.83–3.30	0.153
VC vs. CF	1.47	0.76–2.86	0.253
TKA vs. THA	1.71	0.87–3.36	0.117
CHF	1.58	0.46–5.40	0.470
CKD	0.67	0.14–3.26	0.616
COPD	1.92	0.38–9.60	0.427
Diabetes Mellitus	1.43	0.66–3.10	0.369
HTN	0.80	0.39–1.64	0.547
Alcohol Use	1.28	0.61–2.68	0.513
Substance Abuse	2.62	0.98–6.98	0.054
Tobacco Use	1.56	0.79–3.07	0.201
Emergency	3.58	1.46–8.77	0.005
Inpatient Readmission	11.01	5.47–22.18	< 0.001

OR odds ratio, 95% CI 95% confidence intervals, VC vancomycin and cefazolin, CF cefazolin, ASA American Society of Anesthesiologists, CHF congestive heart failure, CKD chronic kidney disease; chronic obstructive pulmonary disease, HTN hypertension, TKA total knee arthroplasty, THA total hip arthroplasty
^aReferent group: Matched control without corresponding comorbidity

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