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Table 4 Association between COVID-19 and risk of perioperative complications in THA patients. Values are reported as Odds Ratio (95% Confidence Interval)

From: Timing of total joint arthroplasty post-COVID-19: an evaluation of the optimal window to minimize perioperative risks

Characteristic

Odds Ratio

Adjusted Odds Ratio

P

DVT

 CCI > 3

2.53 [2.11, 3.04]

2.88 [2.41, 3.43]

 < 0.001

 COVID Period 0–2 Weeks Before Surgery

5.01 [2.46, 9.10]

4.67 [2.29, 8.45]

 < 0.001

 COVID Period 2–6 Weeks Before Surgery

3.49 [1.36, 7.30]

3.38 [1.32, 7.04]

0.004

 COVID Period 6-12Weeks Before Surgery

2.31 [0.82, 5.09]

2.10 [0.74, 4.61]

0.104

Sepsis

 CCI > 3

4.37 [3.61, 5.32]

4.62 [3.84, 5.58]

 < 0.001

 COVID Period 0–2 Weeks Before Surgery

1.45 [0.36, 3.86]

1.37 [0.34, 3.65]

0.587

 COVID Period 2–6 Weeks Before Surgery

2.41 [0.74, 5.78]

2.38 [0.73, 5.71]

0.089

 COVID Period 6–12 Weeks Before Surgery

0.91 [0.15, 2.86]

0.85 [0.14, 2.67]

0.816

Surgical Site Infection

 CCI > 3

2.08 [1.77, 2.46]

2.11 [1.80, 2.47]

 < 0.001

 COVID Period 0–2 Weeks Before Surgery

1.99 [0.70, 4.38]

1.77 [0.63, 3.88]

 < 0.001

 COVID Period 2–6 Weeks Before Surgery

0.86 [0.14, 2.70]

0.83 [0.14, 2.62]

0.004

 COVID Period 6–12 Weeks Before Surgery

0.97 [0.24, 2.57]

0.97 [0.24, 2.56]

0.104

Acute Kidney Injury

 CCI > 3

5.70 [3.34, 10.04]

5.70 [3.72, 10.03]

 < 0.001

 COVID Period 0–2 Weeks Before Surgery

N/A

N/A

 

 COVID Period 2–6 Weeks Before Surgery

N/A

N/A

 

 COVID Period 6–12 Weeks Before Surgery

N/A

N/A

 

30-Day All-Cause Mortality

 CCI > 3

6.25 [4.28, 9.28]

6.26 [4.37, 9.11]

 < 0.001

 COVID Period 0–2 Weeks Before Surgery

9.03 [3.43, 19.65]

10.83 [4.17, 23.11]

 < 0.001

 COVID Period 2–6 Weeks Before Surgery

13.21 [4.56, 30.33]

11.88 [4.13, 26.95]

 < 0.001

 COVID Period 6–12 Weeks Before Surgery

3.48 [0.57, 11.23]

3.25 [0.53, 10.37]

0.101

365-Day All-Cause Mortality

 CCI > 3

8.96 [7.50, 10.76]

8.85 [7.46, 10.53]

 < 0.001

 COVID Period 0–2 Weeks Before Surgery

4.91 [2.70, 8.34]

5.24 [2.90, 8.73]

 < 0.001

 COVID Period 2–6 Weeks Before Surgery

5.47 [2.72, 9.95]

5.10 [2.56, 9.26]

 < 0.001

 COVID Period 6–12 Weeks Before Surgery

2.60 [1.15, 5.06]

2.40 [1.07, 4.65]

0.018

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