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Table 1 Musculoskeletal Infection Society (MSIS) 2013 Criteria [14]

From: DAIR for periprosthetic joint infections—One week to save the joint?

Musculoskeletal Infection Society (MSIS) criteria

Periprosthetic joint infection is present when one major criterion is present or three out of five minor criteria exist

Major Criteria

• Two positive periprosthetic cultures with phenotypically identical organisms

• A sinus tract communicating with the joint

Minor criteria

• Elevated CRP and ESR

• Elevated synovial fluid WBC count or + + change on leukocyte esterase strip

• Elevated synovial fluid PMN%

• Positive histological analysis of periprosthetic tissue

• A single positive culture