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Table 2 European Bone and Joint Infection Society (EBJIS) 2021 “Infection Likely” Criteria [15]

From: DAIR for periprosthetic joint infections—One week to save the joint?

European Bone and Joint Infection Society (EBJIS) 2021 Infection Likely Criteria

Periprosthetic joint infection is present when there are two positive findings

A + B OR A + C

A

Clinical

Clinical Features

• Early radiographic loosening

• Wound healing problems

• Recurrent fever/ Bacteraemia

• Purulence around prosthesis

A

Clinical

CRP

• CRP > 10 mg/L

B

Laboratory

Synovial fluid

• Leukocyte count > 1500

• PMN > 65%

B

Laboratory

Microbiology

• Single Positive Culture (aspiration or intra-operative)

• > 1 CFU/mL any organism on sonication

B

Laboratory

Histology

• Presence of ≥ 5 neutrophils in a single HPF

C

Radiology

Nuclear Imaging

• Positive white cell labelled scintigraphy