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Table 1 Manifestations associated with early diagnosis of SHA

From: Diagnosis and surgical treatment of chronic destructive septic hip arthritis

Category

Specific manifestations

Symptoms

 Pain

Persistent hip joint pain, aggravated by activity

 Limited mobility

Reduced range of motion in the hip joint, limited flexion, abduction and internal rotation

 Fever

Low-grade or intermittent fever

 Systemic symptoms

Fatigue, loss of appetite, weight loss, etc

Signs

 Swelling

Soft tissue swelling around the hip, possibly accompanied by redness and increased skin temperature

 Tenderness

Significant tenderness in the anterior hip or groin area

 Joint deformity

Flexion contracture (chronic infection)

 Sinus

Skin sinuses accompanied by purulent discharge (advanced stages of chronic infection)

Laboratory Tests

 WBC

Elevated WBC and neutrophil percentage (active infection)

 CRP and ESR

Significantly elevated

Joint fluid analysis

Purulent and significantly elevated WBC (usually > 50,000/mm3)

Gram staining, positive culture and mNGS

Imaging

 X-ray

Joint space narrowing, bone destruction, osteoporosis, periarticular sclerosis and osteophyte (late stage)

 CT

Bone destruction, sequestrum formation and periarticular abscesses

 MRI

Joint effusion, synovial thickening, bone marrow edema and surrounding soft tissue infection

  1. CRP C-reactive Protein, CT Computed Tomography, ESR Erythrocyte Sedimentation Rate, MNGS Metagenomic Next-generation Sequencing, MRI Magnetic Resonance Imaging, SHA Septic Hip Arthritis, WBC White Blood Cell Count