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Table 2 Baseline characteristics of included studies

From: A systematic review of geographic differences in knee phenotypes based on the coronal plane alignment of the knee (CPAK) classification

Studies

Country/

Region

Number of knees

Number of subjects

Healthy or arthritic

Mean age, years (SD/range)

Sex (n, %)

BMI (SD/range)

Study design

Men

Women

MacDessi et al. [5]

Belgium

500

250

Healthy

22 (20–27)

125 (50.0%)

125 (50.0%)

22.0 (2.9)

Retrospective cross-sectional

Australia

500

500

Arthritic

66 (44–88)

190 (38.0%)

310 (62.0%)

NA

Corban et al. [12]

Australia

700

643

Arthritic

68.2 (7.9)

305 (48.6%)

395 (61.4%)

29.7 (5.7)

Retrospective cohort

Tarassoli et al. [35]

Australia

88

76

Arthritic

68 (42–87)

41 (53.9%)

35 (46.1%)

NA

Retrospective

Tarassoli et al. [34]

Australia

465

394

Arthritic

69.4 (46–89)

179 (45.4%)

215 (54.6%)

29.59

Retrospective

Hazratwala et al. [18]

Australia

165

140

Arthritic

65.1 (8.3)

63 (45.0%)

77 (55.0%)

NA

Retrospective case series review

Kim et al. [21]

Australia

1124

1124

Arthritic

NA

NA

NA

NA

Retrospective review

Moore et al. [27]

Belgium

500

250

Healthy

22 (20–27)

125 (50.0%)

125 (50.0%)

22.0 (2.9)

retrospective case–control

Australia

710

355

Arthritic

70.2 (7.6)

162 (45.6%)

193 (54.4%)

29.7 (4.8)

Franceschetti et al. [14]

Italy

180

180

Arthritic

NA

73 (40.6%)

107 (59.4%)

NA

Retrospective cohort

Dragosloveanu et al. [13]

Romania

500

500

Healthy

36.0 (14.2)

330 (66.0%)

170 (34.0%)

26.5 (4.2)

Observational cross-sectional

Romania

500

500

Arthritic

68.0 (7.2)

125 (25.4%)

375 (74.6%)

30.8 (4.0)

Huber et al. [20]

Austria

8739

7456

Arthritic

69.0 (9.3)

2502 (33.6%)

4954 (66.4%)

30.3 (5.6)

Retrospective

León-Muñoz et al. [23]

Spain

501

447

Arthritic

69.9 (6.3)

159 (35.6%)

288 (64.4%)

29.8 (3.9)

Retrospective cross-sectional

Sappey-Marinier et al. [31]

France

1078

936

Arthritic

71.3 (8.0)

780 (83.3%)

156 (16.7%)

29.2 (5.1)

Retrospective cohort

Loddo et al. [26]

France

1240

1240

Healthy

58.9 (14.5)

658 (53.1%)

582 (46.9%)

25.9 (6.3)

Retrospective diagnostic

Pangaud et al. [30]

France

178

178

Arthritic

70.3 (7.1)

NA

NA

29.6 (4.3)

Retrospective cohort

Åženel et al. [32]

Turkey

414

207

Healthy

32.9 (8.4)

109 (52.7%)

98 (47.3%)

NA

Retrospective cross-sectional

Turkey

408

296

Arthritic

54.5 (7.9)

141 (47.6%)

155 (52.4%)

NA

Steele et al. [33]

USA

1946

973

Mixed

61 (9.1)

477 (49.0%)

496 (51.0%)

29.3 (19–44)

Retrospective cohort

Grant et al. [16]

USA

1166

1166

Arthritic

NA

520 (44.6%)

646 (55.4%)

NA

Retrospective

Morrisey et al. [28]

USA

335

335

Arthritic

69.2 (8.1)

135 (40.3%)

200 (59.7%)

NA

Retrospective

Hsu et al. [19]

China

214

214

Healthy

41 (18.6)

111 (51.9%)

103 (48.1%)

NA

Retrospective cross-sectional

Li et al. [24]

China

944

479

Arthritic

67.6 (6.4)

101 (21.1%)

378 (78.9%)

26.8 (3.4)

Retrospective

Liu et al. [25]

China

434

434

Arthritic

66.4 (9.3)

93 (21.4%)

341 (78.6%)

25.5 (3.7)

Retrospective

Gao et al. [15]

China

214

107

Healthy

48.8 (14.4)

41 (38.3%)

66 (61.7%)

NA

Retrospective

China

477

246

Arthritic

65.3 (7.3)

65 (26.4%)

181 (73.6%)

NA

Toyooka et al. [6]

Japan

500

343

Arthritic

75.1 (8.0)

95 (19.0%)

405 (81.0%)

26.2 (4.0)

Retrospective

Nomoto et al. [7]

Japan

248

248

Arthritic

NA

79 (31.9%)

169 (68.1%)

NA

Retrospective cohort

Harada et al. [17]

Japan

300

300

Arthritic

NA

150 (50.0%)

150 (50.0%)

NA

Retrospective cross-sectional

Konishi et al. [22]

Japan

284

231

Arthritic

74.0 (8.0)

33 (14.3%)

198 (85.7%)

26.7 (4.4)

Retrospective cohort

Mulpur et al. [29]

India

500

250

Healthy

26.8 (4.5)

109 (43.6%)

141 (56.4%)

25.8 (4.8)

Prospective cross-sectional

India

500

250

Arthritic

62.3 (8.2)

76 (30.4%)

174 (69.6%)

28.2 (4.0)

Yang et al. [36]

Korea

Korea

500

500

Healthy

23.8 (8.2)

416 (82.2%)

84 (16.8%)

24.8 (8.9)

Retrospective cross-sectional

500

500

Arthritic

75.0 (4.0)

419 (83.8%)

81 (16.2%)

26.1 (4.0)

Coetzee et al. [8]

South Africa

608

344

Arthritic

68.4 (9.2)

76 (22.1%)

268 (77.9%)

NA

Retrospective cross-sectional

  1. NA, not available. BMI, body mass index